Ostarine MK-2866 And Osteoporosis
Ostarine (also known as MK-2866 and Ostabolic) is a selective androgen receptor modulator that is routinely prescribed to patients with health conditions such as osteoporosis.
Let us find out how Ostarine can provide significant relief to individuals who are diagnosed with osteoporosis. Before this, let us learn about this health condition and its causes to gain a clear and complete understanding.
What Is Osteoporosis?
Osteoporosis is a health complication that is characterised by impaired fractured healing and reduced bone mass. Widely viewed as a "women's disease", osteoporosis also affects 20 percent of men. In this health condition, bones get weakened that make them fragile and at an increased risk to break. Osteoporosis develops slowly over a period of many years. It is usually only diagnosed when a sudden impact or minor fall causes a bone fracture.
The most common injuries in people who are diagnosed with osteoporosis are:
- Hip fractures
- Wrist fractures
- Fractures of the vertebrae (spinal bones)
However, the injuries can also happen in other bones like in the pelvis or the arm. At times, a sneeze or cough can also cause a partial collapse of one of the bones of the spine or rib fracture.
Osteoporosis affects more than 3 million people in the United Kingdom alone. Every year, more than 500,000 people receive medical treatment for fragility fractures as a result of osteoporosis.
Factors that increase the risk of developing osteoporosis:
- Low body mass index
- A family history of osteoporosis
- Heavy drinking and smoking
- Long-term use or abuse of oral corticosteroids
- Medical conditions such as malabsorption issues, inflammatory conditions, or hormone-related conditions
- Prolonged use of specific medications that can affect hormone levels or bone strength
Conditions, Diseases, And Medical Procedures That May Cause Bone Loss
There are a few medical procedures and many health conditions that may increase the likelihood of osteoporosis.
The list may include but not limited to:
- Rheumatoid arthritis (RA)
- Multiple sclerosis
- Ankylosing spondylitis
- Gastrointestinal bypass procedures
- Inflammatory bowel disease (IBD)
- Weight loss surgery
- Leukaemia and lymphoma
- Sickle cell disease
- Depression and eating disorders
- Low levels of testosterone and estrogen in men
- Premature menopause or irregular periods
- Poor diet, including malnutrition
- Chronic obstructive pulmonary disease (COPD), including emphysema
- Chronic kidney disease
- Hyperparathyroidism and Hyperthyroidism
How Can Ostarine Help Osteoporosis Patients?
Both men and women face an increased risk of health complications with reductions in bone-protective sex hormones with age. This increases the risk of osteoporosisand poor bone health. The risk of bone fractures can be reduced by increasing muscle mass and bone mineralisation. This is where Ostarinecomes into the picture.
Ostarine helps in improving bone strength and strengthening the skeletal system. By mimicking the effects of testosterone in the bones and muscles, Ostarine prevents bone diseases. According to studies, MK-2866 demonstrates beneficial effects on bone properties, general physical function, and muscle wasting.
In a study, the effects of Ostarinewere studied in a postmenopausal osteoporotic bone in a rat osteoporosis model. During the study, ovariectomy was performed on 46 of 56 3-month-old female Sprague–Dawley rats. Ostarine was orally administered on a daily basis eight weeks after ovariectomy in dosages of 0.04 (low, OVX + Ost. 0.04), 0.4 (intermediate, OVX + Ost. 0.4), and 4 mg/kg (high, OVX + Ost. 4) body weight. Another group of ovariectomized rats received no Ostarine. The effects of intermediate and high dosages were overall compared.
Primarily, improvements were seen in structural properties like bone volume density and bone mineral density. This study also disclosed that short-term treatment of osteoporotic bone with MK-2866 results in improvement of many microstructural bone indices. The researchers said long-term Ostarine treatment has the potential to improve biomechanical properties.
One of the biggest advantages of Ostarine is that the results gained with it are easier to maintain. This is a wonderful advantage and more important than its more apparent and huge muscle-bulking effects. Obviously, there is nothing more worrying for athletes and bodybuilders than losing all the muscle mass gained (shortly after the cycle) after months and years of hard work.
Ostarine users can expect to receive clean, dry, and pure lean muscle gains that are characterised by increased protein synthesis. In addition to these advantages, Ostabolic is also useful to improve stamina, lifting endurance, and strength. It also improves pumps during workouts and the sense of well-being. The best thing is that the use of Ostarine during a SARMs cycle is not associated with post-cycle crashes.