What are prohormones?

What are prohormones?

Prohormones are compounds similar in structure and properties to testosterone and 19-nortestosterone (nandrolone). These are natural precursors of sex hormones or are capable of being converted into their analogs by the same metabolic pathways. Testosterone is a male sex hormone; it gives a pronounced anabolic effect, amuscle mass increase, and affects the nervous system, relieving fatigue and raising general tone and mood.

Simply put, these are drugs that, when ingested, are converted into testosterone.

Prohormones are gaining popularity in fitness and bodybuilding. Thanks to the use of drugs, athletes manage to achieve a positive effect when gaining mass. Reviews show that regular use of designer steroids does not cause negative consequences. The substances do not have pharmacological advantages over anabolic drugs.

Prohormones or Steroids?

At the moment, of course, the best prohormone cannot compete with the effective injectable forms of classic anabolic steroids, but this is a long-term task. It should be noted that now, to increase the anabolic effect, prohormones are used simultaneously in several forms:

  • Some basic forms, usually gel capsules, are used with food.
  • Other forms of powders or tablets to be sucked under the tongue, in the mouth 30-60 minutes before training.
  • Special rubbing and lotions are applied after training to clean skin for transdermal absorption.

And we manage to find such combinations of basic, sublingual, and transdermal forms, which turn out very well.

Another problem is how to keep prohormones in the body. The liver stands in the prohormones way with an almost impassable barrier. After which 80% -90% of prohormones are excreted without reaching the target cells of muscle tissue, where their anabolic activity was planned. So to get an effect comparable to that of 5 mg tablets of methandrostenolone or stanozolol (anabolic steroids with a 17-alpha-methyl group, which pass through the liver and enter the bloodstream), a dose of prohormones of 100 mg or higher  is needed. This problem was solved after creating modified forms of the best prohormone, capable of passing through the liver and becoming available to peripheral muscle tissues, including with the 17-alpha-methyl group.

Features of prohormones

Features of prohormones

Steroid designers, when ingested, are transformed into the main hormone. There are natural prohormones, proinsulin, and thyroxine in the human body converted into triiodothyronine. Experts and doctors say that there is no side effect from drugs, and the human body perceives substances as natural. The main difference between best prohormone and simple anabolic steroids is that the substances are converted to the active form immediately and begin to act. Legal steroids are much more effective, but there is a possibility of negative effects on the body.

Estrogen and testosterone levels decline with age; the same can be said about prohormones. Clinical studies have shown that 5 milligrams a day are enough for women during menopause, and even 10 milligrams a day is ineffective for men. Regular training does not help the situation either. Scientists continued to test drugs, which ultimately led to an effective result. For men, a dosage of 20 milligrams per day is quite enough to achieve a positive result. Prohormones affect the growth of testosterone and estrogen. Women with hormone therapy use the drugs during menopause.

The best prohormones

  • 4-androstenedione is converted to testosterone. Studies show that the conversion rate does not exceed 6%, which means that only twenty of the supplement is converted to testosterone. A high level of aromatization, that is, the likelihood of developing gynecomastia, edema, and other side effects, is high. It has high androgenic activity.
  • 4-androstenediol (4-AD) is converted to testosterone. Conversion rate 15.76%. It is not converted to estrogen. It has less androgenic activity compared to 4-androstenedione since it is not converted to dihydrotestosterone.
  • 19-norandrostenedione is converted to nandrolone (retabolil). Anabolic activity is almost like testosterone. It does not convert to estrogen, and it has low androgenic activity.
  • 19-nor androstenediol, the best prohormone, is also converted to nandrolone. The conversion rate is slightly higher than the previous prohormone.
  • 1-androstenediol (1-AD) is converted to 1-testosterone (dihydroboldenone). Has seven times greater anabolic activity and two times greater androgenic activity compared to testosterone. Almost wholly converted to the active form when passing through the liver. It does not aromatize (does not convert to estrogen).
  • 1,4-androstadienedione (1,4 AD) is converted to boldenone. High oral bioavailability. Low degree of aromatization to estrogen (50% less compared to testosterone). Low androgenic activity.
  • 1-testosterone (1-T) is similar to testosterone. It has four times greater oral bioavailability compared to testosterone and does not convert to estrogen. It is not a prohormone.

You can buy prohormones in the UK. You must purchase these drugs from trusted sellers who only sell quality products.

Prohormones in bodybuilding

Prohormones in bodybuilding

In the past two decades, the best prohormone has been actively used by athletes in bodybuilding, powerlifting, and other strength sports to increase muscle mass and strength. Initially, the main advantage of prohormones was their legal status since they do not formally belong to anabolic steroids. Nevertheless, many prohormones have been listed along with steroids in recent years, and their circulation is limited.

The constant race of the manufacturer and government control leads to prohormones appearing on the market that do not pass any clinical trials. These supplements often have rather serious side effects that are more severe than classic steroids. It should be noted that prohormones have the status of a food additive, which means that the quality control of these products is much lower than that of pharmaceuticals.


Prohormones penetrate deeper into sports, displacing classic anabolic steroids. There are several problems here, but also some clear advantages. The problems lie on the surface while replacing a handful of methandrostenolone tablets with any combination of prohormones is impossible. But the time of methane or stanozolol has passed, they are determined by doping control for several weeks after use, so the risk of getting caught in out-of-competition control is very high.

It is believed that prohormones are less toxic and practically not falsified. At the same time, ordinary anabolic steroids are constantly counterfeited, and now you can no longer even trust verified labels and packages. Studies have shown that the timing of the elimination of prohormones is much shorter than that of conventional anabolic steroids. Androstenediols are not detected whatsoever after a couple of days if the steroid profile is not suppressed due to the excessive use of anabolic steroids of the past.

About Author

I am a gym freak and fitness lover who started to write blogs based on personal experience. Writer by profession and fitness consultant by heart, I can help you transform your body into a better shape and size. My blogs can help you get answers to all the questions you have been looking for when it comes to body transformation. I can suggest you the best supplements for intensive look, muscle gain, fat loss and transformation stacks. Read about the best recommended products along with its benefits and side effects. For any queries you can connect through email.

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