YK-11, also known as Myostine, is rated very highly by professional bodybuilders and strength athletes across the globe. This synthetic and steroidal selective androgen receptor modulator (SARM) has a comparable anabolic activity that is quite similar to anabolic androgenic steroids in nature.
YK-11 was first studied in 2011 by Japanese researcher Yuichiro Kanno. It was found to be a partial agonist of the androgen receptor with gene-selective characteristics. Studies in the past have suggested that YK-11 has better muscle building effects than Dihydrotestosterone (DHT). It has a propensity to act as a Myostatin inhibitor.
What Is A Myostatin Inhibitor?
Myostatin (also called as growth differentiation factor 8) is a protein produced and released by myocytes (a type of cell found in muscle tissue) that act on the autocrine function of muscle cells to inhibit myogenesis: growth and differentiation of muscle cell.
Essentially, Myostatin keeps the body from growing too much muscle. A Myostatin inhibitor like YK-11 inhibits how much of Myostatin is in the body and this allows you to surpass your muscle building and bodybuilding thresholds. In addition to this, YK-11 also has the ability to increase Follistatin, an activin-binding protein, to a great degree. In other words, YK-11 helps the body to produce far significant gains in terms of lean muscle mass that would have been otherwise almost unattainable.
How YK-11 Works?
YK-11 attaches itself to the androgen receptor that prompts muscle cells to naturally produce more of anabolic factors. Unlike most SARMs, YK-11 does not come with limited androgenic effects and leads to dramatic muscle growth. In addition to these advantages, YK-11 also promotes muscle retention, muscle growth, and growth of new muscle cells.
This gene-selective partial agonist of the androgen receptor is well-known for its unique ability to not stimulate any kind of physical interaction between the NTD/AF1 and LBD/AF2 [N-terminal domain (NTD) and activation function (AF); AF1 and AF2 are located within the NTD and the ligand-binding domain (LBD) and regulate the transcriptional activity of the estrogen receptor (ER)] that is required for the complete transactivation of the androgen receptor. YK-11 demonstrates anabolic activity in vitro in C2C12 myoblasts and offers better potency in comparison to dihydrotestosterone (DHT) in this context.
Therefore, it proves out to be a wonderful alternative to everyone who is looking out for a replacement to anabolic steroids that are often fake, sub-standard, and even lead to severe side effects. YK-11 is also an amazing option for fitness-conscious individuals that want to maintain quality and amount of muscles while keeping away from fat cells.
YK-11 And Testosterone-Comparison
Testosterone is a critical hormone found in the human body. It works both as an anabolic steroid and a sex hormone.
YK-11 and Testosterone are quite similar in function and nature. The only underlying difference is that YK-11 is formulated to focus only on specific cells while Testosterone works on most cells in the human body. It is worthwhile to note here that anything beyond the natural levels in the blood can cause undesirable side effects like prostate enlargement. In other words, the use of synthetic testosterone or testosterone injections for a prolonged period is never recommended as the benefits are outperformed by the negatives, especially when testosterone is administered in large quantities.
YK-11 reacts to specific tissues only and therefore its side effects are zero or almost minimal. Moreover, YK-11 can be administered in an oral form that is both relatively safe and convenient when compared to testosterone injections that can lead to abscess formation, sharing of needles, and pain at the injection sites.
Benefits Of YK-11
One of the biggest advantages of YK-11 is that it helps in growing new muscle over those that have already reached the level of genetic limitations. This, in turn, stimulates an increase in the level of muscular corset and hardness.
It also means that heavy muscles of the body are then less susceptible to burnout or deformation even during sessions of cardio training and intense workouts. As a result, workout and training sessions will become longer and more effective and powerful. This will also ensure that the attained results can be easily preserved long after the YK-11 cycle is over.
The use of YK-11 is also associated with great advantages, including but not limited to:
- No anabolic steroid side effects
- Facilitates muscle hardening
- Inhibition of Myostatin levels
- Increase in Follistatin levels
- Better pumps and increased muscular fullness
- Increase in muscular strength and size
- Lean muscle mass gains without fluid retention
- Slows down the ageing process of cells
- Improvement of blood circulation
- Increases endurance
- Promotes fat burning
- Helps you get rid of stubborn abdominal and visceral fat
- Prevents the muscle mass loss during weight loss
- Prevents neuronal damage
- Stimulates intensive muscle mass growth without a rollback phenomenon
- YK-11 can be added to all kinds of cycles for additional energy and muscle growth
YK-11 Dosing Recommendations
The recommended dose of YK-11 is 2-5mg (for women) twice and 5-10mg twice a day (for men), preferably with meals, for a period of 6-8 weeks. Some male users even increase the dosages of YK-11 to 20mg a day over the course of a steroid cycle or SARMs cycle with YK-11 though it is always best to start using YK-11 at a lower dosage in the initial stages and find your own sweet spot. A cycle with YK-11 should always end with post cycle therapy to stay protected and retain gains made with this wonderful SARM.
Half-Life Of YK-11-Tips And Precautions
YK-11, just like most SARMs, are not hepatotoxic since they are non-methylated. Moreover, it is characterised by a high level of oral bioavailability that means YK-11 can easily be ingested instead of being injected. The half-life of YK-11 is approximately 5-8 hours.
It is important to note that YK-11 is not recommended to pregnant and breastfeeding women. YK-11 is also not advised to individuals who are allergic to its active and non-active ingredients. Furthermore, the use of YK-11 should always and only be made for legal purposes under strict medical supervision. The dosages of YK-11 should never be increased without a prior medical recommendation.
YK-11 Storage Conditions
YK-11 is best stored in a dark and cool place, which is away from direct sunlight, heat, and moisture. It is best stored at a controlled room temperature of 0 - 4 degrees Celsius for short term (days to weeks) or -20 degrees Celsius for long term (months to years), unless otherwise specified.
For maximum effect, most bodybuilders and powerlifters stack YK-11 with Ibutamoren (MK-677). The combination of MK-677 and YK-11 creates an ideal environment for significant energy, muscle mass, muscle size, and muscle growth gains. YK-11 is also stacked with Testolone (RAD-140) for experiencing lightening changes in physique.
YK-11 is also stacked with Ligandrol (LGD-4033) that is well-known for inducing significant lean muscle mass gains. If you are planning to run RAD-140 and YK-11 in a cycle of 6-8 weeks, RAD-140 is best used in daily dosages of 15-30mg along with 10mg of YK-11 every day. On the other hand, an ideal LGD-4033 and YK-11 stack is best done with 10-15mg of LGD every day along with 5-10mg of YK-11 every day.
Results with YK-11 are absolutely amazing, to say the least. This is simply because it has anabolic effects on both bone and muscle tissue. It is no wonder that YK-11 is considered by industry experts and users as the strongest SARM available.
The use of YK-11, when complemented with a good diet and intense workouts, can help you easily pack on 10lbs of quality muscle within a period of 6-8 weeks. This muscle gain in such a short period of time actually takes ages to attain in a natural way. Online YK-11 reviews would help you realize the real advantages of YK-11. A big majority of users report unprecedented and crazy muscle mass and strength gains while researching with YK-11.
How To Buy YK-11 Online-YK-11 For Sale
YK-11 can be easily purchased on the internet using safe and secure payment options. However, you must always observe a high sense of care and diligence while making the purchase as there are a lot of fake YK-11 manufacturers online. Buying through them will not only mean you will lose your hard-earned money, but it will also mean that you will be using fake or under-dosed or sub-standard YK-11 that may lead to severe side effects.
Therefore, it is always suggested to buy YK-11 online only from a reputed SARMs seller like the SARMs Store that deals only in premium, research-grade YK-11.