Perfect time To Take SARMs? Well it all depends on the half life.
Selective Androgen Receptor Modulators or SARMs are therapeutic compounds that are known to mimic anabolic agents but are characterised by fewer androgenic properties compared to anabolic androgenic steroids. The fact that SARMs selectively target tissues in a direct way means their use is not associated with steroid-like side effects such as prostate enlargement and kidney damage.
In this piece of information, we will be reading about how to use SARMs, when to take SARMs, and how SARMs work.
Ligandrol (LGD-4033)
Ligandrol, or LGD-4033, can be described as a nonsteroidal Selective Androgen Receptor Modulator that is best taken orally. Originally developed for preventing muscle wasting and increasing lean muscle growth, LGD-4033 helps athletes and bodybuilders reach their muscle mass and fat loss goals as lean muscles are more likely to burn more calories than fat during intense workouts.
The beauty of this SARM is that it effectively binds with very high selectivity to androgen receptors. Ligandrol creates anabolic effects in the bones and muscles after binding with the androgen receptors that results in the growth of more muscle and body strength. Since LGD-4033 does not lead to steroid-like side effects, you don't experience typical estrogenic side effects such as testicle shrinkage, acne, balding, or prostate enlargement.
In terms of safety and research, Ligandrol is presently superior to all of the other Selective Androgen Receptor Modulators with its potency matching and even exceeding that of anabolic steroids. It is worthwhile to note that study results highlighted by the National Institute of Health’s U.S. National Library of Medicine reported human beings can safely tolerate up to 22mg of Ligandrol for 14 consecutive days. The best thing is that participants of the study reported significant improvements in the overall sense of well-being, strength, and lean body mass along with dramatic reductions in body fat.
This SARM has a half-life of 24 to 36 hours and therefore you can take Ligandrol once a day. With Ligandrol, you don't have to ever worry about complex intra-week cycling protocols as you do with other performance enhancing drugs. You can even take LGD-4033 either on a full or empty stomach though it is always suggested to take SARMs with meals and at least 30-45 minutes before workouts. The amount of Ligandrol you should take will differ according to your specific goals.
Bulking: LGD-4033 is best used by men in daily dosages of 10-20mg every day for a period of eight to twelve weeks. For women, the recommended daily dosage is 5-10mg in a cycle of six to eight weeks.
Cutting: LGD-4033 is best used by men in daily dosages of 10mg every day in a cycle of eight to twelve weeks and in dosages of 5mg every day in a cycle of six to eight weeks. You may stack it with other cutting SARMs such as GW-501516, MK-2866, and S-4. Ligandrol is best taken with GW-501516 if your goal is to lose weight.
Recomposition: Ligandrol is best used by men in daily dosages of 10mg every day in a cycle of eight to twelve weeks and in dosages of 5mg every day in a cycle of six to eight weeks. For recomposition purposes, it is best stacked with GW-501516.
It is highly recommended that you should not use Ligandrol beyond fourteen weeks at a stretch. This is simply because the body can get immune to the action mechanism of LGD-4033 and therefore a break of at least 4 to 6 weeks is highly recommended even if you are thinking on the lines of bridging with SARMs.
Cardarine (GW-501516)
Technically, Cardarine (GW-501516) is a selective activator that binds to the Peroxisome proliferator-activated receptor (PPAR)-δ receptors instead of androgen receptors like other SARMs usually do. Despite this underlying difference, GW-501516 provides results that are simply impressive as you would experience with other SARMs as it activates AMP-activated protein kinase or AMPK that is responsible for the stimulation of skeletal muscle tissue, oxidising fatty acids, and glucose uptake in muscles. Cardarine increases HDL cholesterol (the good cholesterol) by an average of 79 percent while simultaneously reducing LDL cholesterol (the bad cholesterol) in addition to burning fat by stimulating fatty acid oxidation.
In research studies, Cardarine has also been used to treat pre-diabetic, obese men with metabolic syndrome where it demonstrated the ability of controlling obesity and reversing metabolic abnormalities. Cardarine has also been used by athletes and bodybuilders as a potent endurance increasing supplement for years now without any reported harmful side effect. In the early studies, Cardarine has shown efficacy to improve angiogenesis in the body that is the ability of increasing vascular body supply to feed cells of the body. This compound has also demonstrated usefulness for inhibiting the growth of cancer cells. In a separate study, Cardarine demonstrated efficacy to build muscle mass and burn fat while regulating type 2 diabetes, lowering Very low-density lipoprotein, and increasing high-density lipoprotein.
The half-life of Cardarine is 16 to 24 hours and this means you should ideally take a daily dosage of 10mg. You should split your dosages into two, taking one dose every 10 to 12 hours.
When it comes to GW-501516 dosing, 10 to 20mg every day for a period of eight to twelve weeks is effective for men when it comes to improving aerobic and anaerobic endurance while also promoting fat loss. A dose of 10mg every day for 8 to 12 weeks is suggested for men to increase endurance while a daily dose of 20mg for 8 to 12 weeks for men is ideal for fat loss. Like with any other SARM, you should start with the minimum recommended dosage in the initial stages and then adjusting the doses depending on your body's reaction to it.
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Nutrabol (MK-677)
Nutrabol, which is also known as MK-677 and Ibutamoren, is a growth hormone secretagogue that induces the secretion of growth hormone in the body. In other words, Nutrabol is a compound that induces the pituitary gland for increasing the production of human growth hormone in the body.
You may have heard about Growth hormone that gets secreted by the pituitary gland. It is responsible for the regulation of variables like muscle growth, bone growth, blood sugar levels, body weight and composition, and metabolism. The production of natural GH by the body declines as you age and this is exactly where Nutrabol comes into the picture.
The administration of an exogenous growth hormone such as MK-677 is known to dramatically improve bone density and exercise endurance. It is also known to enhance exercise capacity, bone composition, and muscle mass. The administration of Nutrabol has the potential of kickstarting the pituitary gland to promote or increase the production of natural human growth hormone in the body.
Let us understand how Nutrabol helps you in three different ways.
- Nutrabol improves the actual, endogenous function of GH-releasing hormone
- Inhibits the signalling of somatostatin, also known as growth hormone-inhibiting hormone (GHIH)
- Reduces somatostatin levels that shut the release of growth hormone
In a study, a therapeutic benefit of MK-677 was discovered. This study revealed Nutrabol promotes nitrogen balance when complemented with caloric reduction. By using Nutrabol, individuals can expect muscle growth and improved ability of the body to facilitate muscle recovery.
Nutrabol is also effective to promote cell generation in the tissues and treating the deficiency of growth hormone. It is also suited for promoting nitrogen balance for building muscle and muscle cell regeneration. Nutrabol is equally effective for reversing muscle wasting disease and improving the quality of sleep.
The recommended dosage of Nutrabol for men is 25mg every day, preferably 12.5mg in the morning and 12.5mg in the evening, preferably with meals and 30-45 minutes before workouts. For women, the recommended dosage of Nutrabol is 10mg every day, preferably 5mg in the morning and 5mg in the evening, preferably with meals and 30-45 minutes before workouts.
Conclusion
Selective Androgen Receptor Modulators are extremely potent drugs that should be handled with great care and diligence. The dosages of SARMs should never be increased without prior medical recommendation. Moreover, these compounds should be used only for legal, medicinal, and research purposes. It is equally important for you to buy SARMs only from a trustworthy source like the SARMs Store. This will ensure that you are only buying research-grade, premium selective Androgen Receptor Modulators from one of the world’s most preferred source of top-quality SARMs so it is easy for you to create and maintain the highest standards of overall health and well-being.